FM Research: exercise and muscle blood flow

Discussion in 'Fibromyalgia Main Forum' started by tansy, Nov 30, 2005.

  1. tansy

    tansy New Member

    in fibromyalgia patients during standardised
    muscle exercise: A contrast media enhanced colour doppler study.

    Eur J Pain. 2006 Feb;10(2):137-44.

    Elvin A, Siosteen AK, Nilsson A, Kosek E.

    ISS Health Care, Sabbatsberg, Radiology department, 113 82 Stockholm, Sweden.

    PMID: 16310717


    The aim of the study was to investigate if contrast enhanced ultrasound
    (US) imaging of muscular blood flow during and following exercise could
    detect alterations in vascularity in fibromyalgia (FM) patients.

    Ten FM patients and 10 matched controls were examined with US during
    standardised static and directly following static and dynamic muscular
    contractions of the infraspinatus muscle. Doppler ultrasound evaluation was
    performed before and after the administration of ultrasound contrast media.

    The FM patients had lower magnitude of muscle vascularity following dynamic
    (p<0.001) and during (p<0.002) static exercise compared to controls. The
    immediate flow response to muscular activity was not only of a lower
    magnitude, but also of a shorter duration in FM patients following dynamic
    exercise (p<0.001) and during static exercise (p<0.01). There were no
    statistically significant group differences in blood flow intensity or
    duration following static contraction.

    In conclusion, contrast enhanced US was found useful to study real-time
    muscle blood flow changes during and following standardised, low-intensity
    exercise in FM patients and healthy controls. Our results support the
    suggestion that muscle ischemia can contribute to pain in FM, possibly by
    maintaining the central nervous changes such as central
    sensitisation/disinhibition. US with contrast can be a new valuable
    approach to assess muscle perfusion in pain patients during standardised
    exercise.
  2. dononagin

    dononagin New Member

    Thanks Tansy.. you know it's good to know that there is people out there studying this!!