To the person who suggested a good way to take Savella, thank you. My daughter has been experiences nausia since she started taking it this week. I agree with the statement regarding Lyrica. The drug companies don't tell the general medical profession that 8% of the US population can't just "cold turkey" off this drug without going through sweats and seizures. A pain management doctor put my daughter on 450 mg (up from our gen. dr's order of 150). This higher dosage has packed on 85 pounds and led to even more depression. Our GP suggested Savella to lessen the Lyrica and help wean her off of the Lyrica. He suggested starting with Savella to replace the AM dosage of 50 mg rather than at night. Thanks again. Mother in Fresno, CA.