Georgetown Research on CFS-Dec 2nd release

Discussion in 'Fibromyalgia Main Forum' started by cosmoo, Dec 4, 2005.

  1. cosmoo

    cosmoo New Member

    Hi,
    Thought people would be interested in this latest reasearch from Georgetown University on CFS. They published a news release on it friday Dec.2nd. Definatly food for thought. FM people are isted here also in the study..

    Here are the instructions for accesing the site.
    Search engine-Georgetown Universtiy News Releases
    When your list comes up click on the one that says "Department of communications (with news releases)."
    When that page comes up click on the small word in the top right hand corner which says"search"
    When that page comes up under A it says "full text search" type in Chronic Fatigue syndrome (in the box).
    When that page comes up go to the 2nd title listed "office of cmu news releases Dec. 2nd, 2005,reasrearch provides more evidence....

    You are there! Sorry for the long instuctions but I don't know how else to get to the article and it's definatly worth reading!!
    Take care
    Cosmoo
  2. elliespad

    elliespad Member

    I did a cut and paste for you.
    ___________________________________________________________
    Office of Communications
    News Releases


    FOR IMMEDIATE RELEASE: December 2, 2005



    CONTACT:
    Liz McDonald
    202-687-5100
    eem6@georgetown.edu



    Research Provides More Evidence That Chronic Fatigue Syndrome Is A Legitimate Medical Condition
    Syndrome Linked to Neurological Abnormalities



    Washington, DC -- Researchers at Georgetown University Medical Center have found that chronic fatigue syndrome (CFS) may be rooted in distinct neurological abnormalities that can be medically tested. Although the sample studied was small, this research provides objective, physiological evidence that the controversial disorder can be considered a legitimate medical condition.

    Chronic fatigue syndrome defines a range of illnesses including fibromyalgia and Gulf War syndrome, all of which have fatigue as a major symptom. Even among medical professionals, there is a disagreement about the causes, diagnosis and treatment of CFS because so much about the disorder remains unknown. One reason CFS is difficult to diagnose is because it shares symptoms with many other diseases, including multiple sclerosis and lupus. Even when other illnesses are ruled out and a CFS diagnosis is given, there is not a standardized course of treatment and it’s difficult for doctors to measure patient improvement. Estimates are that two to four times as many women as men are diagnosed with CFS.

    The Georgetown study, published in the December edition of the BMC Neurology Journal, an online publication, reveals that patients diagnosed with CFS and its family of illnesses have a set of proteins in their spinal cord fluid that were not detected in healthy individuals. These proteins might give insight into the causes of CFS and could someday be used as markers to diagnose patients with the disorder.

    "For years, patients with chronic fatigue syndrome have suffered from painful symptoms for which there is no blood test, diagnosable physical condition or any method for doctors to measure improvement," said James Baraniuk, MD, assistant professor of medicine at Georgetown University Medical Center and first author on the study. "Our research provides initial evidence that chronic fatigue syndrome and its family of illnesses may be legitimate, neurological diseases and that at least part of the pathology involves the central nervous system."

    The disorder is characterized by profound fatigue that is not improved by bed rest and that may get worse with physical or mental activity, according to the Centers for Disease Control and Prevention. Persons with CFS usually function at a lower level of activity than they were capable of before the onset of illness, feeling too tired to perform normal activities or easily exhausted with no apparent reason. Patients also report various nonspecific symptoms, including weakness, muscle pain, impaired memory and/or mental concentration, insomnia and post-exertional fatigue lasting more than 24 hours.

    The study looked at 50 individuals suffering from at least two disorders related to CFS, including fibromyalgia and Gulf War syndrome. By examining spinal cord fluid in patients with CFS and in healthy individuals, the researchers found that CFS patients have 16 proteins that healthy individuals do not. Five of these 16 proteins are found in all patients with the illnesses but in none of the controls. The results indicate that those 16 proteins could possibly serve as a "biosignature" for the disease and could someday be used to diagnose CFS.

    "Although this is a small study and more research on the subject is necessary, these results indicate it might be possible to develop a simple laboratory test to diagnose these disorders in the future," Baraniuk said.

    Other co-authors on the paper include Begona Casado, PhD, and Hilda Maibach, MS, of Georgetown University Medical Center; Daniel J. Clauw, MD, of the University of Michigan; and Lewis K. Pannell, PhD, of the University of South Alabama, Mobile; and Sonja Hess, PhD, of the National Institute of Diabetes and Digestive and Kidney Diseases.

    About Georgetown University Medical Center
    Georgetown University Medical Center is an internationally recognized academic medical center with a three-part mission of research, teaching and patient care (through our partnership with MedStar Health). Our mission is carried out with a strong emphasis on public service and a dedication to the Catholic, Jesuit principle of cura personalis -- or "care of the whole person." The Medical Center includes the School of Medicine and the School of Nursing and Health Studies, both nationally ranked, the world-renowned Lombardi Comprehensive Cancer Center and the Biomedical Graduate Research Organization (BGRO.)






  3. Bambi

    Bambi New Member

    I have yet heard! There have been other promising things posted but THIS is VERY important. Thank you for posting it. NOW if we can just get our doctors to go read it. My printer is down or mine would be getting it in the mail Tuesday!
  4. cosmoo

    cosmoo New Member

    Elliespad,
    Thank you for doing that. I am afraid I am fairly new to computer use. This is my first one (embarassing) and while it is easy use cause it's an e-mac I haven't learned how do what you did yet. Thank-you, Thank-you for making this easier for everyone.
    Cosmoo
  5. kch64

    kch64 New Member