Hi! I'm a new (UK) member with a wife suffering from CFS. My wife's had the syndrome for 15 months. For most of that time she's been bedridden. On her better days she is able to come downstairs for dinner, and maybe to sit/lie on the sofa for a short while, but no more. Her bad days she spends in bed, unable to do more than listen to the radio. Our doctor's been excellent- informed and interested, visiting once a week or so, and my wife is prescribed amitriptyline, which helps- marginally. She also is visited by a homeopathic practitioner and an osteopath, and is on a very restricted diet- no wheat, yeast, sugar. She takes a wide variety of mineral and vitamin supplements. I gave up my job recently, for one which is largely home-based, and we are lucky to have family in the area who are a tremendous support, along with the neighbours. We have two teenage daughters who are generally very helpful around the house (!). In other words, all the support we could want is in place. Nevertheless, it's difficult not to feel that our lives and family are falling apart. I know that that's the deal, and that I'm not the one who's suffering, but I'm finding it hard to sustain the level of both practical and emotional support that she requires. My wife hasn't smiled at me for 15 months, we haven't been out of the house together for that time- no holidays, no day trips etc. She is also (understandably) resentful if I feel I need to get out of the house for a while- unless it's work related, or shopping. After all, she's been confined to the same room for all that time! What can I say to her when she says that she's never going to get better? What's the strategy for keeping any sort of meaningful marriage in these circumstances? Any ideas for further treatments? (Acupuncture gets a good billing in these pages, and we've not tried it- anyone???) Sorry- just having a bad day, I guess!!