I am trying to resolve a lot of gut issues, so I just started taking Glutamine again. I had tried it several years ago but was not on it long enough to see great results. I thought I would try it again and see if it helps. I do know it does some things in my brain, that is evident, I just hope that it does more in my gut. I also decided to research Glutamine, even more, to brush up on what I already new. That is when I came upon an article claiming that Glutamine may not be as benign as once thought. I thought I would share the information and see what others think. http://www3.interscience.wiley.com/cgi-bin/fulltext/113375041/HTMLSTART I just skimmed the article but I believe it does not apply to chronically ill people, like us. However, if the ideas are true, then they will effect everyone's glutamate/glutamine system. So, it may shed some light on why some people have had bad experiences with Glutamine and why some have not been effected at all. This could help resolve one dysfunction pathway and possibly lump some into a certain sub-type. It might also help distinguish those that have a destroyed gut [stress, ABX, NSAIDS, etc.] from those that have possible Enterovirus [or other intestinal] infections. I don't know... I'm under the influence of Glutamine right now, so maybe this makes no sense at all ? I am curious to know what others think.