Great News about XMRV Research

Discussion in 'Fibromyalgia Main Forum' started by spacee, Oct 28, 2010.

  1. spacee

    spacee Member

    This was on the WPI FaceBook site.

    A HIV researcher in Missouri who works with Japanese researchers on HIV says the XMRV
    virus research is explosive (in a good way). He and his colleagues work on finding the
    'lock' (as he calls it) of the HIV strains. Once they find the lock, the key is easy to make.
    Then they are able to make a drug that prevents the HIV from entering the cell.

    They have already found the lock for XMRV!!! That's the great news. These researchers
    have found the locks and keys for HIV in the US, Japan,someplace in Europe and are looking
    for the lock and key to HIV in Africa.

    This is a whole new way of treating retroviruses. The fact that XMRV was so easy to find is
    just fabulous.

    A huge thank you to these researchers and their funding comes from the we got
    the NIH funding this way!

    This is really all I know about it. Don't know how long it will take to make the keys, etc.

  2. mbofov

    mbofov Active Member

    It was on the PH website:

    “Potentially Explosively Important” XMRV Research at University of Missouri
    October 27, 2010

    Work with the XMRV virus is “potentially explosively important” says Dr. Stefan G. Sarafianos, PhD, one of the world’s leading retroviral researchers, based at the University of Missouri.

    And some of the most potentially explosive work is being done in his lab.

    A short time ago, Dr. Sarafianos’s team “solved the crystal structure of an important protein in the XMRV virus – the one that’s essential for viral replication – and accordingly the logical target for future antiviral therapies. That is, they have defined this protein’s intricate shape so precisely that they can now work on creating a molecule that will link into it tightly, so as to block its activity in the body.

    “If we know what the lock looks like,” says Dr. Sarafianos, “we can make the key.” And indeed his lab is working to identify/develop compounds able to prevent XMRV from replicating itself, with the objective of getting “a jump on developing treatment” of any diseases the research community may find it associated with/causing, such as chronic fatigue syndrome and prostate cancer.

    Even more important, the Sarafianos research team has proven its ability to make such keys.

    The U of Missouri Bond Life Sciences Center team is currently involved in a collaboration with Japanese experts to develop antibodies for preventing HIV virus from entering human cells.

    Specifically, the Japanese colleagues have already created an antibody that blocks the type of HIV virus typically involved in cases found in the US, Australia, Europe, and Japan. They’re now forging ahead, with a brand new $400,000-plus NIH grant, to modify the antibody so that it will block the type of HIV typical in Africa.

    To read more about Dr. Sarafianos’s work, read “Unraveling the Mysterious XMRV Virus,” by Denise Henderson Vaugn, at

  3. spacee

    spacee Member

    My brain forgot that WPI directed the viewer to the ProHealth! Thanks for noticing. I love
    to give credit to ProHealth...they do a lot for us.

  4. skeptik2

    skeptik2 Member

    Very good research being done.

    Seems like the virologist BELIEVE in this XMRV, doesn't it?

  5. spacee

    spacee Member

    I love believers!!


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