My reply is not doing what I want it to do, but I just like thank you for your info on Remeron. However, when it was offered to me, I saw myself bulging out of my stretch jeans with many extra pounds on. It was hard enough to accept 40 over the years. But, Remeron apparently is the newer or newest drug for depression, since it has different chemical components, when one takes the extra many pounds into 'stride'. However, I was told that there are newer ones which are coming on the market soon which do not have these unwanted side effects. However, I am on Celexa, to help mostly with the fatigue. The depression is secondary because of the fatigue which comes with it. It ist most helpful for me at the moment after trying everything under the sun. But, herbs will be no alternative for me, but weight gain not either. So, will wait and hope for better meds. Thanks Stormy.