I was told for years that I had FM or Chronic Fatigue. I kept insisting that there was much more to it, and I could explain my symptoms and the reasons. I was an RN, Advanced Nurse Practitioner and Certified Registered Nurse Anesthetist for years before becoming disabled. Finally, Dr. Salvato listened to me, in Houston, TX, and tested me for B lymphocytes and subclasses. All four were low, one a little less than the others. The stimulation test did not get them to budge, so we finally had the answer. I have primary immunodeficiency. Actually, primary humeral immunodeficiency, which is an inability of the body to react to infection by producing the four subclass white cells. I could have a normal white blood count, but no one had ever tested for subclasses. I relate it to someone looking at a dish of pearls, and just counting the total, and then not sorting them as to size. One can have a "normal" white blood count for someone not infected or infected, but without the adequate number of ALL OF THE DIFFERENT SORTS, they may not work. That is what happens in this case, and my doc said they are finding it more and more in patients with a big infection rate who have been diagnosed with FM and Chronic fatigue. It is a mystery to us that I am alive, at age 57, when I was exposed to virulent infectious crap throughout my career. I had some very serious sore throats and infections in childhood and they removed my tonsils and it seemed to improve a little, but they just didn't understand it. Now, most children are diagnosed while in toddler hood or very early childhood. Just a few weeks ago, they had a case on Mystery Diagnosis, and the child nearly died before someone finally checked for it. The primary treatment is to avoid infections, and treatment with immune globulin and aggressive antibiotics for infections. Oh, and once one gets this diagnosis, NOBODY DISRESPECTS YOU, suddenly the doctors who have been telling you that you are a psych case, or it is ALL IN YOUR HEAD, are falling down all over themselves because YOU ARE SO ILL. This goes for SSDI and the disability insurance companies, as well.