Has anyone had luck with Cymbalta?

Discussion in 'Fibromyalgia Main Forum' started by Imfinetoo, Oct 15, 2006.

  1. Imfinetoo

    Imfinetoo New Member

    Tomorrow I start on Cymbalta for my FM. Has this helped anyone? I've been in a flare up since March, and I'm trying everything. Any advice?
  2. NO1NOS

    NO1NOS New Member

    hi imfinetoo,

    im on cymabalta, few months now, its suppose 2 help with pain and depression.

    i dont notice any pain help but i do notice slight depression relief,

    i have to take it mid morning or lunch time (with food) it makes me shaky or anxious id say so the food i guess helps for me. no other side affects bad or good.

    good luck let me know how it works after u take a few to get in ur system.

    best wishes, imfinetoo good one lol,,
    check back soon
    no1nos

  3. Toga

    Toga Member

    And I can honestly say it has helped. I do have some side effects. I get hot flashes with some sweating. (I've got some small fans here and there around the house.)

    I also get a little dizzy about one hour after taking it. I know what's causing it and try to be careful for a while and the spells go away.

    I still have some pain. I also have Osteoarthritis, so I think that accounts for a lot of my pain. The anti-depressant really helps. My attitude towards everything is a lot better.

    I would say try it and give it a good try before giving up. A lot of the side effects go away in the first several weeks and the ones I still have are pretty minor.

    The Fatigue is still pretty bad most of the time. But I don't get as upset about what I cannot accomplish like I used to do.

    Toga
  4. forfink

    forfink New Member

    I just started taking Cymbalta 9 days ago. I've had to break down a 30mg. tablet into 2 doses. I react to new drugs, unfortunately. So far so good, hope to take the whole capsule soon.
    Anyone know how long you had to take it before you noticed a reduction in pain? Also, what dose worked for you? Thanks
  5. JLH

    JLH New Member

    YES, I have!!!

    I have taken it for about 2 years. I can really tell a difference on my pain level. It took a little while, though.

    I started out on 30 mg a day for a few weeks, then went up to 60 mg/day which is my maintenance dose. (My doc wrote a script for 60 mg capsules.)

    However, I found that when I took the 60 mg in the AM, that it caused me to be drowsy all day, and I don't like that feeling.

    So, my doc changed my prescription to get 30 mg capsules, 2 x day. Now, I take one 30 mg capsule in the AM and the other one at bedtime. No more drowsiness during the daytime!!

    I hope the Cymbalta helps you like it does me.

    I also take Neurotin. It also helps me tremendously!


    Hugs,
    Janet
  6. soresue

    soresue New Member

    I have been on Cymbalta for about a year and it DOES help with FM pain. However, as with most antidepressants, you can't just stop it. After a year, I'm starting to feel that I've become tolerant, as I've had worsening flares and occasionally get a weird "rushing", slightly dizzy feeling and sound in my head that is much like when a music CD is just starting up. I thought I was on the verge of having a stroke until the pharmacist said it was from missing a dose (I'd run out for a couple of days). Anyway, as for the pain, you will notice relief but if you don't, please don't just stop the Cymbalta; rather, wean yourself off it slowly.

    I'm about to try yoga, believe it or not, at the recommendation of my PCP and physical therapist. I feel like my system needs "purging" of medications. Good luck with the Cymbalta,
    Best wishes,
    Soresue
  7. fieldmouse

    fieldmouse New Member

    I have been tasking it for a few months. I started on 30mg then up to 60mg. I do think it helps for the moods. I don't get upset or anxious as aften as I did. As for the pain, I also think it helps a little for that. I havn't noticed any side effects from it but I am tired all day and now I am wondering if I should take it at night. After readuing other posts here I am thinking maybe I will try that. Maybe it is why I am tired all day. I don't know. Its early and I have a bad headache and I think I am rambling...Hugs Mick!!
  8. forfink

    forfink New Member

    How long did you take this prescription before you notice some pain relief?
  9. mindbender

    mindbender New Member

    NO! I did read it works better for females. I didn't like it and jumped off it, and when I came back to reality I was told,"don't get off these drugs cold turkey".I just don't like when a drug makes me feel wierd. I take Lyrica now. Some people don't like it. Everyone reacts differently. Unfortunately you have to try them to decide.

    Lee's Summit. what a great place. I'm displaced from KC myself. I love the Chiefs, I think the Steelers beat them yesterday. No? I also love Kansas City MO I'm trying to get back.
    [This Message was Edited on 10/16/2006]
  10. soresue

    soresue New Member

    As someone said, everyone is different - but I found that with the Cymbalta, I noticed a difference in probably a week - some docs will say that's not possible, but hey, that was my experience. Normally antidepressants take about 3-6 weeks to become fully effective.

    I feel like an old lady with all these meds, and sometimes I think half of what's wrong with me is side effects from meds more than a condition itself. I'm beginning the weaning process - on so many things, don't know what variables work and what doesn't.

    Once the pharmaceutical companies figure out what a cash cow this is, you can be sure they'll find a laboratory biomarker for it and develop a med. Right now, as long as the docs can't find something, we must not have anything...
  11. feldspar13

    feldspar13 New Member


    hello, Imfinetoo
    I was on cymbalta for my depression back in May and June. It didn't really help my depression or the pain I was having from a knee injury, if anything it made it worse.I went off Effexor to go on the Cymbalta, while on the Cymbalta is when I got the full bodyaches and this made my depression worse. I have been to an arthritis doc, found out my vit.D was low have taken vit D supplement felt a little better for about 5 weeks, then it came back just as bad now they say I have myalgia but also have must of the tenderpoints of FM, and just want to sleep to make the pain go away. The main thing the doc said to do was to make sure I keep my depression under control but that is had because they are working againest each other.

    Hope cymbalta works for you!
  12. plushpup

    plushpup New Member

    I have been on Cymbalta for severe depression for about 6 weeks now. I take only 40 mg a day at this point, but have found it effective all along, even when I just took 20 mg. I take it in the AM, but do get very tired around 3 or 4 or so each day -- might try to mix it up with the time.

    I also started on 50 - 100 mg. of trazodone at night to help with insomnia, and sometimes I think it's the combo of the 2 drugs that has been so effective. I am, like, REALLY happy. The third part of my "cocktail", which actually predated the cymbalta and the trazodone, is a small dose of Ultram (usually just 50 mg in the AM, sometimes another 25 - 50 mg around 4 or 5 p.m. if I am in pain again). I had been on that for about 6 months.

    So it's the combo of all three, it seems, that has turned me into a vastly different person -- the person I feel I once was, before depression, before pain. I love my new self -- it has given me such a new lease on life.

    Having said that, I really don't like taking 3 drugs every day -- I am scared to stop any of them, since there have been days I didn't take the traz or the ultram, and have regretted it a LOT. (I also take 120 mg of Armour thyroid, but I feel that's natural so it's a little different to me.) But since I am on a low dose of the 3, I guess I am fine for now. My fibro pain is really not as bad, I think, as some of you guys out there.

    Anyway, Cymbalta has been a wonder drug for me, at least when combined with trazodone and ultram. Good luck. I hope you find as much happiness in it as I have.
  13. angelives4him

    angelives4him New Member

    I have taken Cymbalta for about a year. I had my Rhematologist pull me off and the withdrawl is horrible.... Please be careful and wean yourself off very slowly made me hallucinate etc... very bad experience in the withdrawl of medication however the doctor said skip one everyday for five days then quit taking it. This is not a good way to come off the Cymbalta...check with health care provider...and do it slowly make sure you have someone with you... ~angel
  14. Imfinetoo

    Imfinetoo New Member

    Lee's Summit is a great place to live. It's close to so many things. Hope you are able to move back here. If you do, we'll have to start a support group of two.
  15. Imfinetoo

    Imfinetoo New Member

    I've been thinking about taking a yoga class. I've joined a gym, but haven't really gotten started doing anythig yet. Good luck!
  16. Imfinetoo

    Imfinetoo New Member

    In June my pain specialist took me off of everything I was on, some of which I had been on for 7-8 years. I was in complete agreement with him. I managed to get off everything and for the first time in a long time my head felt clearer and I felt better emotionally. However, as with everything, the downside was I couldn't sleep. For weeks it was 3 or 4 am before I would go to sleep. I tried Ambian, which caused so many side effects I had never take it again, plus several other drugs to help me sleep. I've finally had 3 good nights sleep, after going back on Trazadone. I am on Lyrica, Trazadone at bedtime, and now the Cymbalta. I'm praying that I don't get fuzzy headed again!
  17. hob

    hob New Member

    I have been on it for over a year and it has helps a lot with nagging pain and the depression
  18. mindbender

    mindbender New Member

    Consider it done on the group. Don't ask me why I'm here. I'm afraid it will send me into a crash.
  19. mindbender

    mindbender New Member

    I might as well tell you that I take the generic of Elavil for sleep and only took a couple of days to get used to. I take 900mgs a day of Lyrica. Many people think that is extreme, but my pain is severe.

    I now only take Elavil when I need to because Lyrica wears me out, but the sleep quality is not as good as Elavil. I'm not giving advice, unfortunately it's trial & error.

    I take all 900mgs at the same time in the morning because I noticed sreading it out did not prolong releaf. Taking less was no good.

    Hayleycole has a new thread on a parkensons medication that's showing good signs.
    Hey, I will keep in touch. I Love Kansas City Mo. I throw in Missiouri because everyone thinks KC Kansas, and they don't know the difference. KC Missiouri is much nicer.
  20. 69mach1

    69mach1 New Member

    from pharmicist or dr/? i was told i could not. but that was when it first came out about 2 years ago.

    and not for me, sweating like a pig everywhere all the time.take shower and it would be time for another.
    hot flashes and spiked my normal low bp and pulse way up.
    did do a darn thing for any of my pain.
    made me more depressed.
    i would take it in the morning and i would conk out for another 6-8 hours. and not restful sleep either.

    at night i was taking it it would wire me coudln't sleep.

    i tried so hard to stay w/this program of it. but it came down to not helping made me more witchy. and miserable. not too mention the horrific weight gain from it for me.

    now i am back down to a size 4/5 but i havem ore weight i need to lose. i am only 5'2" so a nice size 2/3 is about perfect for me.

    but i have not been exercising for the longest time in my life time. that is another goal of mine to start soon.

    atleast lower legs and cardio...and quit smoking.

    jodie