I am looking for answers. Apparently my doctors are baffled by this, and I can't imagine that this is really that uncommon, but I may be wrong! For the past 3-4 months my legs/feet have become swollen anytime I've been standing for more than 15 minutes. My doc put me on a water pill. The swelling went down tremendously, and I lost 5 lbs--not the 15 he predicted. Suddenly, the swelling began again (though not to the extent of the first time). Additionally, my legs become red (like they are sunburned), and very hot to touch. They also ache; sometimes actually hurt more than ache. My neurologist has no idea why this happens, nor did my GP, nor the internist I used to see. I have fibro/osteoarthritis with a host of other problems/symptoms. I'm about 90 pounds overweight. I take 14 prescriptions each day, and am not able to be very active. All it takes to make it happen is about 15 minutes of standing or a combination of standing/walking/sitting. The only relief is lying down for several hours. Any ideas?