Sometimes i think some of these meds make you feel worse instead of better. As you all know I've been weining off the effexor to start a trial on cymbalta. The doc told me to take 2 for 10 days then 1 for 10 days then 37.5mg for 10 days (instead of 3/day that i've been taking for over a year now). Instead of taking 2 for 10 days on day 8 I started taking only 1. It's day 11 now and I'm having a great day. I have more energy. I'm laughing and joking around at work. Somebody even asked me if I was on drugs or something(just joking). I told them "NO that's the thing I'm not on as many drugs as usual" If I continue to feel like this by Sunday I will probably start on the 37.5mg. I just don't feel like I'm in a drugged fog like I was.