Hello, I am in the beginning of my journey of hypothyroid and low cortisol levels. I try to research but it is so overwhelming. I will try to keep this short but I need HELP. My life is being destroyed. In March of 2009, I was dx as hypothyroid after years of feeling like something was wrong. My doc started me on naturethroid and I felt a bit jittery but still tired so after testing she added synthroid. After a few months, I felt even worse. Very irritable, couldnt concentrate, felt a sense of dread, tired and wound up all at the same time. I would lay down and nap just to escape. After months of that and telling her that something was still off, I finally stopped taking the meds. The first few months after stopping the medication I was tired but not so irritable, anxious or having that dread feeling. But, I had a family problem that caused stress in my life and I started to feel very anxious .. that turned into exhaustion and irritability. I then broke out in a rash so I was given a steriod shot and felt better all over .. not wonderful, but better. I asked to have my cortisol rechecked but had to wait for the shot to get out of my system. Finally 2 weeks ago, my test results came back and they were low. I was excited to think maybe I would start feeling better if my cortisol was treated. So yesterday I stared my compounded Hydrocortisone SR 5mg. I take it mid morning, afternoon and evening. This morning I want to jump out of my skin. I am jittery, anxious, feeling a sense of dread and thinking life is too difficult. So I am wondering if I need to adjust to this medication? Does that feeling go away? Also, we are waiting on my blood work to start treating my hypothyroid again. Is the problem because we are treating only my adrenals and my thyroid is out? I should be getting my thyroid meds tomorrow but now I am scared to take anything. Any help is appreciated .. I am having a horrible morning and scared to pick up my little girls because I am so weird feeling.