I just had shots (Orthovisc) in my knees today. I used to get the Synvisc (with the ground up rooster cones), but after about 4 times I developed an allergic reaction (knees swelled up really big and hurt like heck). The Orthovisc does not contain anything that can cause an allergic reaction. These shots have really helped as they fill in where the cartilage is missing. It's a gell like fluid. I had both knees done. They advise you to stay off your feet as much as possible for the 1st 48 hrs. . . . but, you don't have to stay completely off your feet. I take the two shots (one in ea. knee) every week for three weeks. My dr. says it's less painful. Some ppl choose to take the one big shot instead. It lasts about 6 mos., then you can have it done again. Hopefully someon else who's had the shots can give you information on how they might have done. Hugs, Sharon PS I posted on your Savella Update, but since this is not related to Savella, thought I would post under New Topics . . . maybe, you'll get more responses.