FIRST OF ALL BEWARE OF FENTENYL PATCHES. There are advertisements now about the med on television here in the states of people dying from getting too much med in their system from them. As much pain as I am in and believe me after 21 years it is plenty I will NEVER use fentenyl patches. I take Percocette 10/325 and luckily for me I am allowed 150 a month. My doctor continues to up my meds as needed since I only ask about once very year or so for stronger. I have tried time release morphone but I get a rash and itch and it only lasted 4 hours instead of 12 for me. My doctor recently explained to me using his hands to give a visual as to why the pain increases more after you have taken a med for some time. He did this as I had mentioned that I hoped I would never get to the point that I would need for example, oxycontin and percocette, one for pain and one for break through. He said, "Oh you will in time and here is why." Then he showed me with his hands using his fingers how the pain meds block the pain sensation and that after a certain time on a med the signals from the brain manage to extend around those pain blockers to create more pain and later more. I began on Ultram 50 mg twice a day about 2001. Then went to 4 a day a couple years later. That stopped working so I progressed as follows: Percocette 5/325 twice a day on bad days and Ultram on lower pain days, then to Percocette 4 times a day 5/325, then to 10/325 Perc twice a day, then 10/325 3 times a day, now I am on Perc 10/325 up to 5 a day, usually 2 mornings, one mid day and 2 at night. Now on this regiment for about 6 months and I really am at the point that I could use more but I refuse for at least another year.