http://www.sciencedaily.com/releases/2012/04/120402162546.htm Inflammation is so intertwined with cfs/fm, I thought I would post this. I am certain that very high levels of stress played a big role in my developing cfs/fm. I don't think stress is the only cause by any means, but certainly a piece of the "big picture" in developing cfs/fm. If you are still experiencing a lot of stress, finding ways to reduce that will probably help improve your health. I think tremendous gains in health can be had by re-balancing gut flora and healing a leaky gut. The deeper I get into healing my gut, the more I realize how profoundly messed up it was and still is to some degree. The irritable bowel syndrome I experienced (which was fairly mild) DID NOT reflect the incredible dysfunction of my digestive tract. It is very possible to have dysbiosis and a leaky gut and have mild symptoms or even no symptoms at all. Also, think about the connection stress has to the gut. Stress can cause diarrhea, nausea, heartburn etc. So there is a strong connection with stress and the gut. Maybe something to think about?