Hi All , just wanted to post that after trying everything under the sun for severe narcotic induced constipation I have found a combination that works for me every morning now,. what a blessing!! If you have suffered like I have please give this a try. take 3 senna 8.6mg tabs and 1 100mg capsule colace in the morning and before bed take 3 more senna 8.6 mg tabs. generics are fine. I had these on hand and usually tried taking them all at once at bedtime which sometimes worked but most of the time did not and a friend of mine (who also is on large doses of morphine) said he gets really good results but he said you have to split the dose am and pm, I didnt acutally think it would work but thought I would give it try. IT WORKS!!! No diarrhea,no constipation just get up and have normal bms. Now I know this isnt a great topic and only those that have dealt with this horrible problem will truely appreciate it. I just wanted to share and hopefully help someone else. love and prayers to all!