I would encourage all individuals diagnosed with CFS and FM to be tested for primary immunodeficiency. There are over 100 different forms of it, it is genetic, and most are diagnosed by their teens, with most in early childhood. Let's face it, though, many of us did not have access to advanced medical care which even understood it. It was really ironic, but I was watching Mystery Diagnosis on TV one night recently, because there was nothing else on, and they had a three year old on there who became desperately ill, was treated at a pediatric hospital, sent home, and came back in much worse. They were stumped for a while and he almost died, but they finally tested him and he had the same immunodeficiency which I have. That was in a very highly thought of hospital. It was also ironic for me, since I had been diagnosed relatively shortly before the show. With this problem, one can suffer through, get the infections in childhood and beyond, have antibiotics pushed at you, and then have them end up giving you two, or three courses of antibiotics before it cleared, or one sees relapses. That happened to me. Then, I had a very severe automobile accident, was sexually assaulted at work and went through everything related to that, and suffered a severe fall in my shower and the bottom fell out from underneath me. My body was totally overwhelmed and what appeared to be fullblown CFS and FM was diagnosed. Now, twelve years after being through the mill, and I knew what to say, how to describe my problems, how to deal with the medical system, since I was an RN, Advanced Nurse Practitioner, and Certified Registered Nurse Anesthetist for 20 years, and I still couldn't find the right doctor and get the right tests until now. The testing consists of doing a Lymphocyte differential. One's total white count can be normal, as was mine. However, there are different kinds of white blood cells, and the testing must look at the subclasses. In my case, it was the B cells, of which there are four types, and all of mine were low, with three being very, very low. Then, they do a stimulation by injecting one with a test to stimulate infection and see if the cells rise as they should. If they do not, then they know that one cannot manufacture enough, and one has an immunodeficiency. There are other subclasses which can be tested as well. It is just a blood test, no radiation or pain involved, and it is worth its' weight in gold. If you have trouble with a doctor in getting the testing done, DEMAND THAT THEY REFER YOU TO A HEMATOLOGIST, IMMUNOLOGIST, OR EVEN AN ALLERGIST, for the testing. It may save your life and your standard of living. For one, you can get adequate treatment, usually with IV IG's or IV immune globulins, and NO ONE CAN DENY YOU ARE DISABLED, so those insurance companies and SSDI cannot deny any longer, as well. I would encourage all of you to obtain this testing. Not everyone with CFS or FM diagnosis will have it, but my physician, who is a specialist for CFS and FM, AIDs, immunodeficiencies, etc. has told me that they are finding it more and more and may begin to include it in their second set of testing. Additionally, most of the immunodeficiency patients have low vitamin D and B12, and I am taking treatment for both and I think it is helping. Once again, I encourage all to be tested and find out for your health and for some respect.