This is a quote from Ian Lipkin-an avid CFS/ME scientist and researcher. Regarding the gut microbiome- http://phoenixrising.me/archives/21929 I like that he pointed out that there could be 3 different types of microbes causing the immune dysfunction, in the gut of cfs/me patients. They could be fungal, bacterial or viral. Causing 3 separate types of immune dysfunction. He also says that the gut is probably not the only source of the immune dysfunction in cfs/me- but that treating the gut "could tackle a very substantial proportion of cases."