I had an appointment with my fantastic primary care doctor yesterday. She is always running an hour or more behind but she will sit and talk to you for as long as you want her to about anything you have concerns about, so she's absolutely worth the wait. I have had a 9:00 appointment before and not gotten out until after 1:00. Anyway, I mentioned to her that I have had more relief from the gabapentin than I've ever had from opiate type medication (which she said means my pain is coming from my nerves being pushed on by spasmed muscles, rather than coming from my bones and joints). Anyway, I've been taking gabapentin for three months now and have gained 10 pounds in spite of excercising A LOT. She said that she didn't want to take me off the gabapentin since it is helping me, but she suggested we add topamax (which is another anticonvulsant, like gabapentin) on top of the gabapentin). I wasn't having complete relief anyway, so instead of upping the gabapentin, adding the topamax should help me have more relief, and either mitigate the weight gain or even give me some weight loss. I have to admit I've actually "lost" three pounds since yesterday already (but that's because I was experiencing some pretty major gastrointestinal distress --blush). My husband started taking topamax last year for bipolar disorder and lost forty pounds in a matter of months and has kept it off pretty easily, so I'm very hopeful.