Does chronic fatigue syndrome pertain to immune activation in all cases? Do many/most/some people with CFS have slightly elevated white counts? Mine is always slightly elevated and boy do I feel it!! I'm also wondering if chronic fatigue runs the same course, for the most part, regardless of the source it begins from. (Whether it was stress, accident/trauma, vaccine). Just being on this board I can tell we all have similarities and differences in our cases. I'm interested in feedback. Also very interested in anyone who was successful in finally lowering their white count.