I just read an article by Dr. Cheney that says that TF 560 is an immune modulator, and that the dosage of Immune Modulators has to be varied so that the immune system doesn't get used to it. With that being the case, should I be taking 3/day for 3 months, then one/day, or should I be on an entirely different schedule? Interesting to find out that the AHCC, which I had taken for years and which stopped working, is also an Immune Modulator. I took 1 capsule, 3 times/week. That makes me think if I could come up with a way of altering the dosage it might start working again! I went off of it entirely the entire month of November, and when I started taking it again in Dec. it worked for 3 weeks, then I went into the relapse I'm in now. This information I read today explains why it quit working! Maybe I'm closer to a solution here! Any opinions? Also, does anyone know if the TF 540 and TF Essentials are Modulators, also? Thanks!