In depth symptom description for Bartonella. Thought I'd share..

Discussion in 'Lyme Disease Archives' started by Manaleon, Jul 27, 2008.

  1. Manaleon

    Manaleon New Member

    I find this interesting because these were my exact symptoms after a tick bite.

    Clinical Manifestations

    Trench Fever

    Trench fever, also known as 5-day fever, quintana fever, or
    Wolhynia fever, is defined as infection of human blood by B.
    quintana. The disease is communicable by means of Pediculus
    humanus, the human body louse. Infection is thought to be
    conveyed from lice to humans via the arthropod excreta, which
    enters the body through broken skin. We have summarized in
    the following section the various clinical aspects of trench fever
    described by Byam et al. (18).
    The incubation period for trench fever is between 15 and 25
    days. This incubation period was reduced to less than 9 days
    when infection was experimentally induced in volunteers following
    their inoculation with a large volume of a preparation
    of crushed infected lice. Reduction in the volume of the preparation
    inoculated resulted in a longer incubation time of 16
    days for the disease.

    Clinical manifestations of trench fever may range from
    asymptomatic infection to severe, life-threatening illness.
    “Classical” trench fever, the presentation most often reported
    among troops, corresponds to a febrile illness of acute onset
    and of a periodic nature often accompanied by severe headache
    and pain in the long bones of the legs.
    However, the sudden development of a wide range of symptoms
    can indicate the onset of trench fever. Such symptoms
    include headache, weakness, pain in the legs, malaise, dyspnea,
    giddiness, pain in the loins, shivering, abdominal pain, diarrhea,
    constipation, anorexia, nausea, frequent micturition,
    restlessness, and insomnia. The prodromal period may last for
    2 days or more. The severity of symptoms increases gradually
    over the first few days of disease. Headache is most often
    severe, especially at the front of the head and behind the eyes.
    When occipital, it is often accompanied by a stiffness of the
    neck, and symptoms may therefore suggest meningitis. Pain
    may spread to the back and limbs, with leg pain being the most
    severe. This pain is often felt in the bones, specifically in the
    tibia. The patient will suffer regular cycles of profuse sweating
    and then shivering. On examination, the tongue is often slightly
    furred, and conjunctival congestion and a decrease in the pulse
    rate in relation to the severity of the fever may be present.
    Areas of tenderness are associated with the pains involving
    muscles, tendons, bones, and joints. The spleen often becomes
    palpable.
    The pyrexia associated with trench fever is often periodic,
    although the cycles may be of irregular duration. The level of
    the pyrexia is also variable, and there may be a relationship
    between the degree of pyrexia and its duration. The interval
    between attacks of pyrexia is usually between 4 and 8 days, with
    5 days being the most commonly observed period. The term
    “quintan fever” refers to the 5-day recurrences. Usually each
    succeeding attack is less severe than its predecessor, although
    in profound cases the patient becomes weaker and leg pains
    become more persistent.

    Major polymorphonuclear leukocytosis often accompanies
    the febrile stages of the disease. Anemia may also occur, especially
    in chronically ill patients.
    Although trench fever often results in prolonged disability,
    no fatalities have been recorded. Patients are most profoundly
    ill during the early stages of the disease, which usually continues
    for 4 to 6 weeks. A minority of illnesses will become
    chronic, during which time the following signs and symptoms
    may develop: exhaustion, headaches, recurrent limb pains, irritability,
    nervous manifestations such as depression, abnormal
    response to stimuli, tendency to sweat, coldness of extremities,
    fever, anemia, and loss of weight. The chronically ill patient
    often also complains of breathlessness on exertion, palpitations,
    pain over the precordium, giddiness, and disordered
    activity of the heart. Damp weather exacerbates all pain. In
    some cases, the infection is very persistent and acute febrile
    lapses occur months after quiescence. Byam et al. (18) defined
    chronic trench fever as “a state of marked debility, with or
    without attacks of slight fever and aching, and characterized by
    a hyperexcitability of the nervous system in general.”

    CLINICAL MICROBIOLOGY REVIEWS, July 1996, p. 273–292 Vol. 9, No. 3
    0893-8512/96/$04.0010
    Copyright q 1996, American Society for Microbiology
    [This Message was Edited on 07/28/2008]