I first got sick nearly 10 years ago. It followed my discontinuing four years of therapy on SSRIs. I'd never had any fibro symptoms until about four months after I stopped taking these pills. After six months of struggling wiht debilitating illness (and tests to rule out Lupus, AIDS, MS) I started taking low doses of doxepin to stop the burning pain. This helped for years with only occasional flare ups. Then a few years ago, I decided to give SSRIs a try again following the birth of my son. Finally went of them a few months ago and suddenly am having a bad fibro relapse. Lots of burning pain. This all got me thinking. Did the long term use of SSRIs cause some molecular changes in my brain that increased the propensity for fibro pain. Just wondering if any of you first experienced fibro pain following a long term prescription of SSRI's -- where you took either Paxil, Prozac, Zoloft et al. for more than a year.