Hey guys . . . dont't know if you've already seen this, but it sounds like this relates to hypercoagulation . . . Terri Blood cells may hold key to fatigue syndrome, doctor says. The shape of red blood cells could hold the key to treating chronic fatigue syndrome, a Dunedin doctor believes. Lack of knowledge about the syndrome's causes and changes it made in people's bodies had probably been the greatest obstacle to developing a treatment, Les Simpson said. After discovering chronic fatigue sufferers' blood did not filter easily, he examined the shape of their red blood cells more closely. He found red blood cells in humans and animals had six different shapes but people suffering from chronic fatigue had more flat shaped cells than usual. When feeling well, they had the same number as anyone else, Dr Simpson said in the magazine New Zealand Family Physician. Dr Simpson studied 2200 blood samples from people with chronic fatigue in four countries. The shape changes "were not a benign event", he said. Flat red blood cells did not flow as easily through capillaries (minute blood vessels). That meant having too many flat cells reduced the flow of oxygen and nutrients, carried in blood, to body tissues. Sufferers of chronic fatigue could have widespread problems including difficulty remembering things, tiredness and intolerance to exercise. Because treatment could not increase the diameter of capillaries, treatment of chronic fatigue syndromes should probably focus on increasing the flexibility of flat red blood cells, Dr Simpson said. Evening primrose oil or fish oil could help the cells become more flexible by increasing the fluidity of the cells' membranes, but the oils did not help everybody, Dr Simpson said.