I know some doctors resort to combining a SSRI with a Tricyclic antidepressant when a single antidepressant alone is not working. I am taking Lexapro, but it is too stimulating. Has anyone had success combining antidepressants? It seems like this could be tricky since many of the tricyclics like Amitriptyline and Doxepin are rather sedating, while the SSRI's like Paxil, Zoloft, Celexa, and Lexapro can cause over stimulation. I would appreciate anyones personal stories or ideas about using two antidepressants. I need all the information I can gather. - Thanks!