Last March my primary doctor said my platelets were too high (785) and sent me to a hemotologist. The doctor says I have essential thrombocytosis. He put me on Agrylin, 2 pills daily. In a week the platelets went down to 240. He had me take one pill daily and they went up to 695 so he increased the medication to two pills daily. I have shortness of breath and fast heartbeat. I'm wondering if this is caused by FMS and not the essential thrombocytosis. I think the platelets are high from the FMS. Anyone had this problem?