I tested positive for ANA in an RA panel about 3 years ago. Tonight my daughter just called and said she'd just got the news that she too has a positive ANA and elevated sed rate. I am worried for my daugther. Is there a genetic link? Her doctor is also considering CFS and/or FM as alternatives to RA or Lupus. My rheumy keeps finding the positive ANA, but other tests continue to be "mixed." So FM is the only consistent problem for me.