I have a new thing (for me anyway). Whenever I exercise, my thighs start itching to the point that I end up with hives and welts. I did a search on Google"itchy thighs" and on about.com there is info that says its like an allergic reaction. It says some people blood gets so heated that it triggers pushing out histamines. Site advised taking an antihistamine before exercising. I was on the treadmill walking. I started taking anthistamine and rubbing on anti-itch cream. It seems to control it now. I did not want to go to the doctor again plus pay a copay. I was just wondering if anyone else had experienced this.