Hello. I have been on minocycline antibiotics for about 3 months now for a mycoplasma infection. My doc said my numbers were higher than anyone he has every seen (he practices integrative medicine). He said I would be on them for 6 weeks-6 months. I know the latest research says at least 6 months, so I have shared that with my doc so I am continuing to take them for 6 months. How do you know when it's time to come off? Do you come off "cold turkey" or wean yourself off? I have heard of some herxing from coming off. I herxed when I went on them, but what would make me herx from coming off? Thanks for the information! Have a blessed day!