Yahool News is carrying a story from AP on new research. Lab studies and genetic findings show measurable differences in CFS patients. "Among their findings: Chronic fatigue patients tested with high levels of allostatic load, which is a stress measure of hormone secretions, blood pressure and other signs of wear and tear on the body. The patients were about twice as likely to have a high allostatic load index as people who did not have chornic fatigue syndrome. The researchers also found that certain genetic sequence variations in five stress-moderating genes showed up consistently in chronic fatigue patients. And they identified at least five subtypes of chronic fatigue syndrome, classified according to criteria that include their genetics and the way their symptoms unfold. "Because we have this information, we're going to be able to predict who is more susceptible to certain types of stressful events," said Suzanne Vernon, molecular biology team leader for the CDC's CFS Research Laboratory in Atlanta. Chronic fatigue syndrome is a complex illness characterized by at least six months of severe fatigue that is not helped by bed rest. Patients also report such symptoms as muscle pain and impaired memory. The cause has never been identified, and there are no specific tests for it. It was first identified in the 1980s, but many people — including some health professionals — have greeted CFS patients with skepticism, regarding it as the complaint of "a bunch of hysterical upper-class white women," said Reeves, who heads the CDC's CFS research program. The CDC research joins a cluster of studies published in the past eight months that implicate certain genes and gene expressions as a contributing factor to the condition, said Kim McCleary, president of the Charlotte, N.C.-based Chronic Fatigue and Immune Dysfunction Syndrome Association of America. The findings contribute to an evolving, complicated explanation of how genes, stress and other factors work together to cause and perpetuate the illness, she said."