I have had terrible leg pains all while on valcyte. They are getting worse and I am not sleeping at night. I'm taking Ultrum, tylonel, and Gabapatin to help. My doctor also switched my anti-depressent to Cymbalta to see if it would help the pain. I'm worried about all the harshness these meds are doing to my liver. I also do not want to be on heavy duty pain killers for the next 48 days worth of valcyte I have. Someone mentioned that Neuropathy is a side-effect of Valcyte. So I have been wondering if I may have it. My dad who is in the Oncololgy field said that chemo causes neorpathy and that the patients take Glutamine for it. I am trying to figure out what ot do and how to handle this pain. They Icy Hot is just not cutting it.