Hello. Has any FM person had a bad experience with taking lexapro for depression and smoking marijuana? I have FMS for 7 years now. A long time ago, I smoked and had the giggles for hours. That was when I wasn't in treatment for depression. More recently, however, I feel like a complete lifeless shell. I've been on Lexapro for 5 months, and I have smoked twice during treatment. Both times I felt ok, interesting hallucinations and sensory experiences, but the day after I felt so tired and couldn't stay awake. I felt completely wiped out and back into a funk. I guess my experience isn't too positive, but what about others? merci.