I was on Prozac and switched to Lexapro. I have been on Anti-depressants since I was a teen-ager and find it has enhanced my life. My mother was bi-polar and I inherited the depression side. Lexapro works well for me. I also was on Lyrica and gained substanial weight so I went back on my Neurontin and increased my dosage to 600 MG 3 times a day it has helped. I also am taking guaifenisin. Is anyone else trying this? Good luck to all of us with FM. It is a daily struggle.