I have CFS. Several months ago I also developed insomnia. Here's what I've tried Ambian CR. This is the time release. With this, I am often able to sleep through the night. Problem is, if I use it a few times it starts to make my depression almost unbearable during the day. Ambian. Not time release. Gives me three or four hours of sleep. No noticeable depression increase. Lunesta. I remember having broken sleep, but I think it was steady sleep for the first three hours. I realize that medications affect different people differently. But if anyone knows of something that usually lasts through the night, please let me know so I can ask my doctor about it.