I don't know if this is tied in to taking bupropion, or if it is due to FMS. I have had NO appetite for ANYTHING for months. When my stomach starts rumbling, I basically force myself to eat -- nothing sounds appealing to me. This afternoon my husband offered me a chocolate cupcake, and I REFUSED!! WTH!? Those are my favorite! But no appetite. Granted, I have to lose maybe like 5-10 pounds, but this is not the way. Anybody else have this problem? Any solutions?