I know there are a couple of people here like me who have low T-cell counts - mine are in the 300 range. I'm prone to viral infections (flu-like exacerbations) that last from weeks-months on top of the usual CFS malaise. These feel bad but what concerns me is the risk for opportunistic (odd) infections - much like what HIV patients get when their CD4 counts dips below 200 - as you can get much sicker and die from them. From Spacee here, I heard that NIH did some work with this in the 1990s but I haven't been able to find the data yet. What I hope to know is, if you are or were like me: 1. Did you or anyone you know with this get an opportunistic infection? I heard that Cheney saw a couple people before with this and opportunistic infections. 2. Did anything appear to help with the T-cell count - e.g. did your doc monitor it and you saw it change with some therapy? Or did the T-cell count seem to gradually rise on its own? How long was it from the time you were low to it rising again? 3. If your CFS improved, did your T-cell count improve with it? I haven't found any published written reports about opportunistic infections and CFS - doesn't mean they don't exist though which is why I'm posting here. Thanks.