Hi Lucky! Hope you are having a decent day! I must be brief, gotta get going, but want to say... St John's wort is actually like a drug, if you get the right preparation. perhaps the study you mentioned used a pill that was not made well. That's why I pay the big bucks for the Neurapas which is a standardized product that HAS been shown in a double blind study to have beneficial effects, and was recommended to me by my friend who had good results with it. I did have good results also, when I took it about 2 years ago, but in order to really feel 'happy" I needed to take about 8 - 10 pills a day [of the previous formulation] and that worked out to over $100 per month. So when money got tight I went onto an SSRI which I got for free with my ODSP coverage. The neurapas now has a new formula, unfortunately they had to take out some of the other very beneficial herbs [corydalis, California poppy, and one more I think] due to new regulations and it doesn't seem Quite as good, but anyways,... that's my take on the St. John's wort thing...I'd be interested to see the study you read and am disappointed to hear that might give many people the impression that SJW not at all helpful. I think many ppl DO get some benefit, I know some personally and I don't think it's placebo effect. It probably doesn't help everybody, just like anything... Melatonin - yeah on it's own wouldn't help me enough for a decent night's sleep either...but I do find the sublingual form helpful for if I wake up too early. I bite off about 1/4 of the tablet and let it dissolve under my tongue and it can help me get another 2- 3 hours of sleep sometimes, without being hugely groggy when I wake up, cause it's absorbed faster and moves out of body faster than the pills. melatonin is broken down by light, so I make sure not to be around much bright light and even will wear an eye mask if it's light in the bedroom. A doc with a special interest in CFS [Dr. Kerr] tuned me in to the fact that some people benefit from lower doses of melatonin than they do with the recommended dosage and I seem to be one of them. A small amount works better for me than a larger amount. The doc showed me a graph from a study and it seems for some ppl, the effectiveness does not increase with a larger dose, but actually decreases at some point. Esp with seniors. She mentioned it when I found that taking regular melatonin capsules at night wasn't helping me and in fact I was getting little uncomfortable shocks in my brain. I know other people get them too, sometimes from other med's. I had a friend who was going to the US pick me up the subl melatonin there, but I think there are a couple of pharmacies here in Toronto that will sell it if you ask them quietly for it. What do you take for sleeping? As you may know, I take restoril, at least for now, but hope to get off it in the future. Have a great weekend, Lucky!!