I was just increased to 100mg three times a day. I have been on it for 6 months and was on 75mg twice a day then 75mg three times a day. The only side effect I see thus far for sure is that it makes me sleepy. My lower back pain continues and may even be a little worse. The fibro and spinal stenosis makes it awfully hard to make it day to day but I try for a positive attitude. I appreciate any sugestions or comments. Sounds like I may need to go to a higher dose. I have had fibro since 1994.