Following my urine test at Great Smokies, the results give no indication of mitochondrial dysfunction. I have a problem with 'malabsorption' of food and a problem with 'neurotransmitters'. They make some suggestions as to what I should do, and what I should take, but my clinician is now convinced that because the mitochondial dysfunction didn't materialise, I don't have M.E and yet everything I've felt and read about over the last eleven years tells me otherwise. Please, if anyone does have any insight into what the hell is going on please help !!