I was attempting to herx using the OLE and thought I was doing ok with it all. However, I developed a really severe sinus infection so quickly after (just today) and have really been feeling pretty miserable most of the week since beginning the OLE. I haven't had a sinus infection in about 3 years, since I have been going to an allergist and receiving immunotherapy injections for the specific antigens that I am allergic to (a number!). Now, I'm not sure what to do. I stopped the OLE. I saw my doctor today, and she placed me on Cipro and gave me a cortisone injection to ease the inflammation. I have had one terrible week with all kinds of new symptoms and just wanted relief. I didn't tell my doctor about the attempt with OLE to herx. Maybe I was just a little scared to tell her (?). I have seen so many posts on the message board about how Cipro and cortisone are "bad" for people with FMS, but then noted the post by Madwolf in Nov 2002 regarding Cipro, and that post made be feel so much better about taking the Cipro! Thanks Madwolf. However, I'm still not sure about the Cortisone and would like some more "expert" opinions on this issue. I was absolutely desperate when I saw my doctor and before I did the search on this site regarding Cipro and Cortisone. Guess I’m just a little confused, tired, miserable, and scared about this dd and need to vent my insecurities. My questions: 1. Will the cortisone negatively affect my illness? 2. What about my immunotherapy shots; should I continue? I haven't heard much about this type of therapy and how it could negatively or otherwise affect my FMS. My FMS doctor (internist) believes that there is no problem continuing with them. Any help with these questions would be appreciated. Thanks.