I'm very frustrated right now - and my dogs don't seem to have the answers or suggestions to help me through this so I'm calling a "SOS" to all of you... With the majority of medications I have tried to date, their effectiveness suddenly stops within 7-10 days. It doesn't matter if it's for sleep, pain, inflammation, etc. Obviously this isn't like taking something long term and working up a tolerance level so an increase of dosage is needed. Or at least I wouldn't think that could happen in just a week's time! It is so frustrating because I finally find relief and think "this is it! it really helps!" and literally overnight it's done...over...finished. If I do increase my dosage it never works. It's so bizarre. Anyone else experience this on/off switch??? Thanks in advance for your reply!