In addition to a very simple multivitamin - Centrum - i have added a multimineral complex - i simply use cheap Holland and Barrat but Nature Plus is really good also - they are both chelated which means they are easier to absorb. I also use a good ammount of Himalayan Pink salt which has rare earth elements - but you can also buy rare earth elements separately which i might do soon. But i think the salt in itself may help too. i simply mix some with a lemon drink to make a sort of Gatorade tasting stuff. The results are nothing short of a miracle. I have had ME for four years diagnosed. I got mine after dancing 4 hours a day for a year. I was so happy then - crash. Pain all over my nerves this fatigue that never ended, sleeping twelve hours a day then waking up worse than before i slept. i have tried everything - all that i could afford. must have easlly spent 20.000 pounds on supplements, herbs, mega mega doses of vitamins, magnesium, guiafenesin, vitamin bs of every sort and type, Q 10 acupuncture, antioxidants, Micheal Maes protocols, probiotics - each one more expensive than the one before!!! I did hours upon hours of research to no avail. every time getting so excited about something new - then it doesn't work. Booooo horrible. i had tried minerals but usually just a one or two at a time - which seemed to make no difference. So many hours of research I lost two beautiful boyfriends cos they could not accept my obsession with trying to cure myself. I simply would not believe that there was no way out. I had to find a way out of the hell and somehow I knew that there was a biological cause to it - not only a psycho-spiritual one. Although this is part of the picture. Now I have been on this regimen i described above for 2 months and the results were slow but impressive. I wake up in the morning and feel alert. i can sit and meditate without needing to lie down or feeling that i did not have the strength to keep myself upright!! I have now been reading about widespread mineral deficiencies in industrialised countries due to mineral soil depletion and artificial fertilisers. The state of our soil is sooo sooo poor. As us greedy humans do we use our soil to the maximum and do not put back the stuff we have taken out. We use artificial fertilisers to increase crop yields but they only contain 3 minerals - nitrogen, potassium and phosphorus - which is what plants need to grow big (but not necessarily healthy). The problem is that humans need many many more minerals than that. Even though some of the minerals are only needed in minute quantities they are essential for health. Organic farming is somewhat better - in that they use natural fertilisers - however they still try to get maximum yield from their land which still means soils end up depleted. Why do some of us get more sick than others because of this? Why have I - who eats in a more healthy fashion - got more sick than my pizza eating friends? Who knows! Its very hard to understand these things. possibly i absorb minerals a little less or a have a susceptibility to fatigue whereas my friends have a susceptibility to other things. Well has anyone else had a positive effect to taking minerals????