Minnesota – Marshall Protocol, mycoplasma, and vitamin D Dr. Nicolson, I'm curious to know your thinking regarding the Marshall Protocol, which Dr. Trevor Marshal developed to treat sarcoidosis, and certain people with chronic fatigue syndrome and fibromyalgia. I believe his protocol involves reducing the bacterial load of mycoplasma, and he maintains that avoiding all sources of vitamin D is essential to do this. What are your views on this, especially given all the news about vitamin D's benefits? Do you know of any research in the past few years that may substantiate or argue against this? Reply: Some patients with Mycoplasma species appear to respond well to the Marshall protocol and some do not. I have no idea why this occurs, but it could be due to other infections, other events, as described above in other replies, or even that some patients require some Vitamin D for their recovery.