New Article on Xyrem and growth hormone

Discussion in 'Fibromyalgia Main Forum' started by SandraD, Aug 19, 2003.

  1. SandraD

    SandraD New Member

    Thought I would pass this on. It is an article I read today from the drug company on Xyrem. It is being used for fibro. It also mentions the growth hormone.

    Orphan Medical stated that it has begun development of a new patent-protected formulation of Xyrem. The Company is evaluating formulation alternatives that could extend the activity of a single Xyrem dose from the current two-four hour range to a six-eight hour range.

    During 2003, the Company expects to begin a proof-of-principle study to evaluate Xyrem for symptomatic treatment of Fibromyalgia Syndrome (FMS), a chronic condition that is estimated to affect as many as six million individuals in the United States. Fibromyalgia Syndrome is characterized by widespread pain in joints, muscles, tendons, and other soft tissues. Other symptoms include persistent fatigue, headaches, cognitive or memory impairment, morning stiffness and non-restorative sleep. The cause of fibromyalgia is unknown, although an imbalance in growth hormone production may play a role. Studies have demonstrated improvement in symptoms in FMS patients given growth hormone. In addition to increasing restorative sleep, Xyrem may be a growth hormone secretogogue and may therefore produce symptomatic relief. The Company does not expect results from this proof-of-principle FMS study until the second half of 2004.


    [This Message was Edited on 08/20/2003]