My doctor wanted me to take CoQ10 200 milligrams. I bought a supplement from the health food store and took just 100 milligrams, I felt like it kept me up at night and I didn't notice any difference in my pain levels or fatigue. I started taking Andre Lessman's CoQ10 at 100 mg's just about two weeks ago, I couldn't believe how well I responded to his supplement. My fatigue level had dropped so much after only two weeks of taking this supplement. Today, however, I have crashed. My fatigue is very bad, BUT I have been able to do so much more since I took the CoQ10, it really has helped me. Although, I have been going non stop since Friday, very busy with cleaning the house, shopping for my mom, visiting a few friends, paying all the bills, and actually went to an outside shopping center on Saturday, usually that is a big NO NO for me, my body just can't handle those outside shopping malls with all the people and commotion. I was in and out of stores for about 4 hours. I was taking advantage of my unusual energy. I think I just overdid it and it's my typical fibro body screaming at me to stop. I am feeling shaky, weak, TMJ flared up, feeling slow, more pain, and of course the moodiness that comes along with it. Very busy and unusual weekend for me But, I normally I could NOT do all that I did, so maybe it's the CoQ10 that has helped me with the energy and stamina, but with this NASTY NASTY fibro you still have to be careful no matter what. I will just have to pace my energy, sounds strange. I won't stop taking the supplement because I feel it is high quality and was recommened by my integrative doc and I feel it will help in the long run. No matter what I take, I still have this horrible condition and have to be careful. Just wanted to share if anyone is taking CoQ10. I am hoping that the CoQ10 will help with pain as well if I continue to take it. Hugs, Chelz.