Hey Everyone! I am usually on the Depression message boards, but I suffer from migraines and was gathering some info for an insurance appeal I am doing. I am subscribed to the peer-reviewed medical journal Current Pain and Headache Reports (costs to subscribe) when I came across this brand new April article and got excited about its potential for FM sufferers (some of you come to the Depression message boards). My heart has always gone out to FM sufferers. This is my good deed for the day (night)! Hope it helps someone if you can find an alternative doc with a hyperbaric oxygen chamber. I live in a rural area and we have a "quack" like that here -- just got to look and find one! Here's the abstract and an excerpt. I thought the science behind this study made a lot of sense 'cause I know how ya'll have those sore points on your body that make you hurt. Good luck to all! --Kelly Hyperbaric Oxygen Therapy in Chronic Pain Management [abstract] Senol Yildiz, MD, Gunalp Uzun, MD, and M. Zeki Kiralp, MD Corresponding author: Senol Yildiz, MD Department of Undersea and Hyperbaric Medicine, Gulhane Military Medical Academy Haydarpasa Training Hospital, 34668 Kadikoy, Istanbul, Turkey. Current Pain and Headache Reports 2006, 10:95-100 Current Science, Inc. ISSN 1531-3433 Copyright © 2006 by Current Science, Inc. Chronic pain is one of the frequently encountered clinical problems that is difficult to cure. Hyperbaric oxygen (HBO) therapy has been reported in chronic pain syndromes with promising results. In this review, we focus on the effectiveness of HBO in fibromyalgia syndrome, complex regional pain syndrome, myofascial pain syndrome, migraine, and cluster headaches. HBO may be beneficial if appropriate patients are selected. HBO is a reliable method of treatment. However, physicians performing HBO must be aware of oxygen toxicity. Another problem regarding HBO is the scarcity of centers administering it. Further research is required focusing on the optimal treatment protocol, the cost/benefit ratio, and the safety of HBO in chronic pain management. ----------------------- EXCERPT: When the circulation is compromised, the resultant ischemia lowers the concentration of adenosine triphosphate (ATP) and increases the concentration of lactic acid. Increased oxygen delivery to the tissue with HBO may prevent tissue damage in ischemic tissues by decreasing the tissue lactic acid concentration and helping maintain the ATP level. HBO therapy causes hyperoxia by raising oxygen concentration far above physiologic levels in all tissues during treatment. This breaks the hypoxia-pain vicious circle in FMS patients. A randomized, controlled study was performed on 50 FMS patients in our clinic, with 26 patients being classified as the HBO group and 24 analyzed as the control group. The patients with FMS in the HBO group were given 15 90-minute sessions at 2.4 ATA over 5 days, and patients in the control group breathed air for 90 minutes at 1 ATA. At the end of the study, the number of tender points in patients, visual analogue scale (VAS) score, and pain thresholds were used in evaluation. The number of tender points in patients with FMS who received 15 HBO sessions declined, VAS scores decreased, and there was a statistically significant increase in pain thresholds.