I have been suffering for many years from fibromyalgia. I also have a blood disorder called von Willebrand's disease which limits the medicine they can give me for treatment b/c my blood doesn't clot properly. For years now they were only giving me muscle relaxers and vicodin which was like popping a tic tac. The muscle relaxers just made me tired and grouchy. I am now on Norco (doesn't even give me 50% relief) and Zanaflex (which does help some but I have to go to sleep). I went to the pain management doctor today and they suggested Savella. I have flat out refused Lyrica due to so many reports of substantial weight gain. I agreed to try Savella and being very optimistic. I'm very curious about others experience with Savella... good or bad. I'm at the end of my rope. I wake up hurting and go to bed hurting. It has drastically changed my life. I'm not active and I'm not enjoying my children as I once did. Some days I can hardly make it up our stairs and I'm only 39! I want to be normal again and live an active, productive life. Please advise!! I look forward to the responses.