New Viral Research for CFS

Discussion in 'Fibromyalgia Main Forum' started by jarjar, May 31, 2006.

  1. jarjar

    jarjar New Member

    U.S. Newswire

    Potential Animal (Zoonotic) Virus Identified in Patients with
    Chronic Fatigue Syndrome, Multiple Sclerosis and Epilepsy

    5/31/2006 12:00:00 PM

    To: National Desk

    May 31 /U.S. Newswire/ -- Recent independent
    scientific research funded by the National CFIDS Foundation, Inc.
    (NCF) of Needham, MA provided preliminary confirmation of a new
    virus identified in patients with Chronic Fatigue Syndrome. The
    Foundation's medical research dovetails with that completed to date
    by Cryptic Afflictions, LLC (1), a private company.

    Dr. Steven J. Robbins, virologist and Chief Executive Officer of
    Cryptic Afflictions, LLC has discovered a major neuropathogen
    identified as an RNA virus designated as Cryptovirus. Substantial
    clinical and molecular evidence indicates that this virus is
    involved in the development of neurological disorders that include
    Chronic Fatigue Syndrome (CFS), also known as Myalgic
    Encephalomyelitis (M.E.) by the World Health Organization, Multiple
    Sclerosis (M.S.) and Idiopathic Epilepsy of unknown cause.

    According to the company, "This previously undetected virus appears
    to be of significant importance to researchers looking for a cure to
    Multiple Sclerosis and many other neurological illnesses. Antibodies
    to the newly discovered virus were found in the cerebrospinal fluid
    and blood of over 90 percent of the patients tested with Multiple
    Sclerosis. It is believed that this newly discovered virus may prove
    to be responsible for a host of neurological disorders. Tests are
    currently being prepared for tissue samples of lesions within the
    brains of patients with Multiple Sclerosis. This will be the final
    round of tests before approaching the FDA for approval of the
    diagnostic tests."

    Dr. Robbins' evidence includes the presence of virus-specific
    antibodies in the serum and cerebrospinal fluid of patients
    suffering from these disorders, the ability of the virus to cause
    virtually identical disease in experimentally-infected animals, and
    nucleotide sequence data that indicates that the virus is pandemic
    and represents a single virus species much like measles.

    A recently published medical journal article suggests that
    Cryptovirus is most similiar to Parainfluenza Virus-5, a rubulavirus
    in the paramyxovirus family. Another rubulavirus related to
    Cryptovirus and Parainfluenza Virus 5, that has gained national
    attention for its large outbreak, is the mumps virus. Rubulavirus
    infections have been associated with encephalitis, meningitis,
    orchitis, inflammation of the testicles or ovaries, spontaneous
    abortion, and deafness.

    The NCF has conducted its own preliminary research into the
    potential role of Cryptovirus and Parainfluenza Virus-5 in Chronic
    Fatigue Syndrome. Professor Alan Cocchetto, Medical Director for the
    Foundation stated, "Our own funded research first confirmed the lack
    of a vital protein, known as Stat-1, in the blood of patients with
    Chronic Fatigue Syndrome. Stat-1 plays an indispensable role in
    immunity. Without this protein, patients are unable to effectively
    fight viral and bacterial infections. Thus, the next logical
    question to be answered was 'Could a virus be causing this Stat-1
    depletion?' " Cocchetto continued, "Parainfluenza Virus-5 is a virus
    that had to be seriously considered as a possible piece of this
    medical puzzle because it directly targets and destroys the Stat-1
    protein." Gail Kansky, President of the NCF stated, "Once we
    determined the status of Stat-1 in patient blood samples, we knew
    that we had to look for possible evidence of Parainfluenza Virus-5
    infection. It was during this phase of our own research that we
    actually learned of Dr. Steven Robbins' discovery of Cryptovirus
    specific antibody reactivity in patients with CFS." Dr. Robbins had
    tested fifty- six serum specimens from patients who had been
    diagnosed with CFS along with eleven matching cerebrospinal fluid
    samples obtained from physicians in Brisbane and Southeast
    Queensland. Dr. Robbins had determined that 96 percent of the blood
    samples and 91 percent of the spinal fluid samples tested positively
    for Cryptovirus specific antibodies in these CFS patients.

    The National CFIDS Foundation's own research began to dovetail with
    that of Dr. Robbins. Scientists funded by the Foundation performed
    numerous tests for Parainfluenza Virus-5 that included antibody as
    well as PCR specific probes. Antibody testing provided some initial
    hints, however a PCR specific probe picked up the infection in a
    former patient of David S. Bell, M.D. and Paul R. Cheney, Ph.D.,
    M.D., both considered well known specialists in the field of Chronic
    Fatigue Syndrome. Kansky commented, "Though our funded research
    continues in diagnostic testing, our findings have served to
    highlight the important work of Dr. Robbins and the role of
    Cryptovirus and Parainfluenza Virus-5 infection in CFS."

    NCF scientists utilized the NIH Genbank database to find the
    nucleotide sequence for a specific viral protein of Cryptovirus that
    matched 100 percent to the porcine (swine) strain of Parainfluenza
    Virus-5 known as the SER strain.

    In 1994, scientists at Bayer AG in Germany first isolated the SER
    strain from swine with Porcine Reproductive and Respiratory
    Syndrome. "This may represent a zoonotic process since zoonotic
    viruses are those that can be transmitted between animals and
    people" stated Cocchetto. Kansky commented, "Here we have what
    appears to be the same viral strain of Parainfluenza Virus-5 on two
    continents and in two different populations, swine and humans. Given
    that the NCF found Parainfluenza Virus-5 in one CFS patient in the
    United States certainly raises the bar." The Foundation is currently
    funding further research.

    The National Institutes of Health (NIH) has several ongoing grants
    in the Parainfluenza Virus-5 field. Currently, however, there is
    only one U.S. scientist specifically funded for research on the SER
    strain of Parainfluenza Virus-5 by the NIH.

    ---


    [This Message was Edited on 06/01/2006]
  2. alaska3355

    alaska3355 New Member

    This is good info- it seems like everyday we get closer to discovering what causes CFIDS and that's a hopeful sign! Terri
  3. Mikie

    Mikie Moderator

    This is very interesting and I'm glad researchers are looking for these stealth infections. I think it is this line of research, coupled with genetic research, which will lead to a cure or, at least, better treatments.

    Love, Mikie
  4. Juloo

    Juloo Member

    It's silly to be this excited over something like this, but I was worried that they'd give it a completely stupid name (that again undermines the whole CFS credibility).

    But CRYPTOVIRUS sounds so Da Vinci Code-esque and sinister -- maybe they'll take it more seriously!
  5. carebelle

    carebelle New Member

    Do I understand that they think CFS/FM is caused by a virus that comes from hogs?
    My grandparents had Hogs and I use to ride them like a horse and help to feed them.
    Do they think it is passed threw eating pork?
  6. ruby711

    ruby711 New Member

    wow! thanks for sharing this info. Very interesting-gives us some hope.
    ruby
  7. Tantallon

    Tantallon New Member

    Good info Jarjar, thanks for posting.

    Sue
  8. ANNXYZ

    ANNXYZ New Member

    I am no science person, but have a gut feeling that most " autoimmune diseases " are in FACT chronic infections that the immune system is attacking .

    It bothers me that researchers have not investigated pathogens more as underlying cause for autoimmune conditions . This is good news and I thank you for sharing it !
  9. Danielle

    Danielle New Member

    Some CFS patients have recently been given an antiviral that is curing them. It's a very potent antiviral.

    Danielle
  10. carebelle

    carebelle New Member

    Boy, that could explain a lot.
    Why I've put on so much weight .
    Why My skin is really pink.and my nose holes are big.
    Sometimes when I laugh, I'll snort.
    I've even been ask if I am related to Ms.Piggie
    We are both blonde's

    I get silly when I'm excited about something.
    Ok now to be serious, How does a virus Jump from a hog to a human?
    Wouldn't that mean it could be passed from human to human?
    I do have Chronic Fatigue Syndrome, and Epilepsy among several other problems.
    Please keep us informed on any news about this.I live about 45 min.from NIH I'd give them my blood to test. Shoot I'd even give them my extra fat who knows what lurks in our fat.Maybe the vaccine will help us loose weight to lol sorry I'm getting carried away again



  11. Mikie

    Mikie Moderator

    There are some viruses which can infect animals and humans alike. A lot of viruses start out by infecting just animals and then mutate to a strain which can be passed from animal to human. This virus can then mutate to a strain which is passes human to human. This is the basis for the worry about the Bird Flu. Originally, it was only in birds but it mutated to a form which can infect people who have been around infected birds. If it mutates to the human-to-human strain, a pandemic will likely ensue.

    In fact, there are some cluster outbreaks in people which may be evidence that it has mutated. These outbreaks are in an area where officials will not cooperate with world health orgs., so no one knows for certain if it has mutated yet. Vaccines cannot be made until it does mutate and by then, vaccines will not be available fast enough to innoculate everyone. There is also a chance that once it mutates, it may burn itself out before killing millions of people.

    I haven't finished reading "Lab 257" yet but I highly recommend it. It deals with these exact issues.

    Love, Mikie
  12. mom4three

    mom4three New Member

    I raised pigs for show in highschool..
  13. jarjar

    jarjar New Member

    I slopped Hogs at step grandparents on occasions...HA!
  14. findmind

    findmind New Member

    Thought I was seeing double...just posted a response on the thread carebelle started about this very same topic...

    One of you should delete your thread so we can discuss this on only one.... carebelle, you have the least responses (?)

    Thanks, luvs...
    findmind
  15. jarjar

    jarjar New Member

  16. Mikie

    Mikie Moderator

    This is good info and it doesn't matter that there are two threads. That way, more people are likely to see it and that's what's important.

    Love, Mikie
  17. findmind

    findmind New Member

    So right, Mikie, didn't think of that!!

    So sorry, please forgive..

    findmind
  18. Mikie

    Mikie Moderator

  19. morningsonshine

    morningsonshine New Member

    How do you feel about vaccines? Why do we alway jump there to immediately solve health problems?

    There has to be other good ways to deal with viruses.
    I feel like vaccines are like playing with loaded guns, after reading about how they are made.

    We are injecting our bodies with so much lethal garbage, it's bound to effect some of us negatively.
  20. woofmom

    woofmom New Member

    It's affecting everyone. But, for some, the harmful effects haven't shown up YET.