I don't really know how long I have had CFS. I remember suspecting it a long time ago. Then I got divorced and every time I went to the doctor he brushed my fatigue off as depression from the divorce even though I was happier than I ever was in my marriage (hence the divorce, which was my choice). Anyway, I also have hypothyroidism since I was about 23, polycystic ovary Syndrome, and I have suffered intermittently from DPU aka Delayed Pressure Urticaria, which is also an autoimmune issue. I have had allergies my whole life, and I was wondering if anyone had heard of these things being tied together. I am scheduled to see a Rheumatologist for the first time this month. My doctor finally thinks I have CFS, and my bloodwork came back with a positive rheumatoid factor and a low positive lupus factor. I have no rash on my face...is it possible to have lupus with no rash? I know the low positive doesn't necessarily mean I have lupus, but I am curious. I don't see the doctor until Oct. 31, so I am anticipating it impatiently. Also, my PCP noted that I have had mono before, which I had been unaware of, and I wonder why he mentioned that. Anyone with insight or experience? I thought dealing with PCOS and hypothyroid was enough to deal with. I am a 28yo Female. (stb 29) I have been gaining weight due to hormone issues with the PCOS and thyroid, not to mention the fatigue robbing me of energy for keeping active. I was once a marathon runner and was in prime physical shape. It is hard to cope with this kind of existence. Any support is welcome and appreciated.