Hi there, I'm 36 and live in the UK. Have just been diagnosed with psoriatic arthritis (having had psoriasis for 29 years). I am to see my consultant in two weeks with a view to going on Methrotrexate. Not too happy about going on it with the side effects. Have heard it makes you quite nauseas, gives mouth sores, makes you really tired and can affect your liver/kidneys?! Also the only joint affected is my wrist (started 6 months ago) but it is not really painful - have had to take ibuferon on the odd occasion, that is all. Is there anyone on Methotrexate with psoriatic arthritis? Does it start off mild? Has any one any info? Been on other message boards and so far have not had any feed back - please reply!!